Mebeverine Hydrochloride and Chlordiazepoxide Tablets

Product description:Mebeverine (antispasmodic) and Chlordiazepoxide (benzodiazepine). Mebeverine works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. On the other hand, Chlordiazepoxide works by increasing a chemical messenger known as GABA (nerve-calming agent) activity in the brain, thereby decreasing nerve cells’ abnormal activity. Thus, together it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort-

Indication:-

• Irritable bowel syndrome (IBS) management,
• Reducing abdominal pain
• Treatment of gastrointestinal spasms
• Enhancing digestive comfort

 Mechanism of action:-

Mebeverine is a musculotropic antispasmodic agent that acts directly on smooth muscles of the gastrointestinal tract to relieve spasms without affecting normal gut motility. Chlordiazepoxide is a long-acting benzodiazepine that enhances GABAergic activity in the central nervous system, providing anxiolytic, sedative, and muscle-relaxant effects. It helps relieve anxiety, which is often a trigger or aggravator in functional GI disorders.

Common side effects:- 

• Drowsiness or sedation (due to chlordiazepoxide)
• Dry mouth
• Dizziness or lightheadedness
• Mild GI discomfort

Storage

store in cool and dry place , keep out of reach of children , store at room temperature below 28°C.